Fattyjunkfooddestroysthebraincellsthatcontrolweight,leadingtoaviciouscircleofobesity,scientistshaverevealed. 科学家通过研究揭示了垃圾食品对健康的危害：因为热量超标的垃圾食品会破坏大脑中控制体重的...Fatty junk food destroys the brain cells that control weight, leading to a vicious circle of obesity, scientists have revealed.
The findings may explain why it is so hard for fat people to shift the pounds.
Researchers fed rats what they described as a 'typical high-fat American diet' and found they had doubled their calorie intake three days later.
Further study showed they also had an inflammation in the hypothalamus, the part of the brain containing neurons that control body weight.
This inflammation stopped a few days later but then recurred after four weeks.
Lead researcher Dr Joshua Thaler, of the Diabetes and Obesity Centre of Excellence at the University of Washington in Seattle, said scientists also detected a healing response to brain injury called gliosis.
He said: 'Gliosis is thought to be the brain equivalent of wound healing and is typically seen in conditions of neuronal injury, such as stroke and multiple sclerosis.
Dr Thaler said: 'The possibility that brain injury may be a consequence of the over-consumption of a typical American diet offers a new explanation for why sustained weight loss is so difficult for most obese individuals to achieve.
'It is not yet clear whether this presumed neuronal injury is permanent, but it may contribute to weight gain.
'If new medicines can be designed that limit neuron injury during overeating, they may be effective in combating the obesity epidemic.'